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Solving complex CDR3 cases

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@mikessh mikessh released this 06 Sep 21:30
· 207 commits to master since this release

Non-canonical CDR3 workaround

  • Fix CDR3 end calculation when J segment reference point is at the boundary or J segment conserved residue is absent with downstream J sequence aligned
  • Implement CDR3 start calculation in case V-CDR3 region was not identified by IgBlast
  • Add "canonical" CDR3 flag which tells if CDR3 starts with C and ends with F/W
    • Add corresponding filter to output (--allow-noncanonical)