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# ComMet (COMparison of METabolic states)
<img src="commet_logo.png" width="250" align="right" />

# ComMet (COMparison of METabolic states) [![DOI](https://zenodo.org/badge/291652692.svg)](https://zenodo.org/badge/latestdoi/291652692)
ComMet is a method based on genome-scale metabolic models for comparing different metabolic states

## Features
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- identification of metabolically distinct network modules
- visualization of network modules as reaction and metabolic map

## More information
Sarathy C et al. Identifying characteristic features of metabolic states using genome-scale metabolic models [version 1; not peer reviewed]. F1000Research 2020, 9(ISCB Comm J):1047 (poster) https://bit.ly/2GvgZsV
## Dependencies
Please follow the instructions on the respective pages
### Toolboxes
- [COBRA](https://github.com/opencobra/cobratoolbox/)
- [Icasso](https://research.ics.aalto.fi/ica/icasso/)
### MATLAB functions
- [insertrows](https://nl.mathworks.com/matlabcentral/fileexchange/9984-insertrows)
- [knee point](https://nl.mathworks.com/matlabcentral/fileexchange/35094-knee-point)

## Preprint
Sarathy C et al., ComMet: A method for comparing metabolic states in genome-scale metabolic models. bioRxiv, Cold Spring Harbour Laboratory. 2020. https://doi.org/10.1101/2020.09.14.296145

## Poster
**Awarded Best Poster at ISMB 2020 (SysMod COSI)**

Sarathy C et al., Identifying characteristic features of metabolic states using genome-scale metabolic models [version 1; not peer reviewed]. F1000Research 2020, 9(ISCB Comm J):1047 (poster) https://bit.ly/2GvgZsV

- Video summary: https://bit.ly/ISMB20_CS
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