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fix: correct uniprot ID of YCR024C
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edkerk committed Oct 28, 2024
1 parent 074fcc1 commit 6cd738f
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Showing 4 changed files with 9 additions and 4 deletions.
7 changes: 6 additions & 1 deletion code/modelCuration/v9_0_2.m
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Expand Up @@ -112,7 +112,8 @@
% To resolve MET17 causing methionine auxotrophy
model = setParam(model,'lb','r_0815',0);

% THI4-thiamine & HOM2-methionine and threonine...
% To resolve THI4 causing thiamine auxotrophy and HOM2 causing methionine
% and threonine auxotrophy
model = removeReactions(model,'r_2070',true,true);
model = removeReactions(model,'r_2071',true,true);
rxnsToAdd.rxns = generateNewIds(model,'rxns','r_',2);
Expand All @@ -135,6 +136,10 @@
% To resolve URA2 causing uracil auxotrophy
model = changeGrRules(model,'r_0250','YJL130C or (YJR109C and YOR303W)',true);

%% Issue #372. Correct UniProt identifier of YCR024C and YCR024C-A
geneIdx = getIndexes(model,'YCR024C','genes');
model.geneMiriams{geneIdx}.value = {'P25345'};

%% DO NOT CHANGE OR REMOVE THE CODE BELOW THIS LINE.
% Show some metrics:
cd(fullfile(codeDir,'modelTests'))
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2 changes: 1 addition & 1 deletion model/dependencies.txt
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@@ -1,4 +1,4 @@
MATLAB 24.1.0.2568132 (R2024a) Update 1
libSBML 5.20.2
RAVEN_toolbox commit 166bc4f
RAVEN_toolbox commit c90390e
COBRA_toolbox 3.4
2 changes: 1 addition & 1 deletion model/yeast-GEM.xml
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Expand Up @@ -170685,7 +170685,7 @@
<rdf:Description rdf:about="#YCR024C">
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource="https://identifiers.org/uniprot/P32903"/>
<rdf:li rdf:resource="https://identifiers.org/uniprot/P25345"/>
</rdf:Bag>
</bqbiol:is>
</rdf:Description>
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2 changes: 1 addition & 1 deletion model/yeast-GEM.yml
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Expand Up @@ -120621,7 +120621,7 @@
- id: "YCR024C"
- name: "SLM5"
- annotation: !!omap
- uniprot: "P32903"
- uniprot: "P25345"
- !!omap
- id: "YCR024C-A"
- name: "PMP1"
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