CONTRIBUTING.md states:
PRs must not be merged with pending reviews. If the PR author decides to make any substantial changes that go beyond of what the reviewers already approved, they can re-request an already accepted review after updating the PR.
In practice, this is not followed often. Personally, I treat the reviewers list as an ANY(codeowner) list, and if I actually care about getting specific approvals from specific people, I try to clearly specify it in the PR body (e.g. "This cannot land unless @sffc has looked at the whatever-whatever code"). Other team members seem to do the same.
We should discuss this policy, and change it if it is not serving us.