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1 | 1 | Lambda: the Local Aligner for Massive Biological DatA
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2 | 2 | -----------------------------------------------------
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3 | 3 |
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4 |
| -Lambda is a local aligner optimized for many query sequences and searches in protein space. It... |
| 4 | +Lambda is a versatile local aligner that can perform protein, nucleotide and bisulfite searches. It... |
5 | 5 |
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6 |
| -* is highly compatible to BLAST (bitscore and e-value statistics, tab separated and verbose output formats) |
| 6 | +* is highly compatible to BLAST (bit-score and e-value statistics, tab separated and verbose output formats) |
7 | 7 | * is much faster than BLAST and many other comparable tools
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8 |
| -* supports many other input and output formats, including standards-conformant ``.sam`` and ``.bam`` and many compression types |
| 8 | +* supports many other input and output formats, including standards-conforming ``.sam`` and ``.bam`` and many compression types |
9 | 9 | * has special features for species annotation and taxonomic analysis
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10 | 10 | * is well-documented and easy to use (e.g. provides progress-bars and memory usage estimates)
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11 | 11 |
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@@ -39,32 +39,32 @@ Before you can search, you need to have an index. You can
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39 | 39 |
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40 | 40 | ::
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41 | 41 |
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42 |
| - % bin/lambda2 mkindexp -d db.fasta |
| 42 | + % bin/lambda3 mkindexp -d db.fasta |
43 | 43 |
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44 | 44 | *(in case you want to create a nucleotide index, instead use ``mkindexn``)*
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45 | 45 |
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46 | 46 | After that running Lambda is as simple as
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47 | 47 |
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48 | 48 | ::
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49 | 49 |
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50 |
| - % bin/lambda2 searchp -q query.fasta -i db.fasta.lambda |
| 50 | + % bin/lambda3 searchp -q query.fasta -i db.fasta.lambda |
51 | 51 |
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52 | 52 | *(in case you want to perform a nucleotide search, instead use ``searchn``)*
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53 | 53 |
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54 | 54 | For a list of options, see the help pages:
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55 | 55 |
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56 | 56 | ::
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57 | 57 |
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58 |
| - % bin/lambda2 --help |
59 |
| - % bin/lambda2 COMMAND --help |
| 58 | + % bin/lambda3 --help |
| 59 | + % bin/lambda3 COMMAND --help |
60 | 60 |
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61 | 61 | Advanced options are available via ``--full-help`` or the man pages, and more documentation is available
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62 | 62 | in the `wiki <https://github.com/seqan/lambda/wiki>`__.
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63 | 63 |
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64 | 64 | authorship and copyright
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65 | 65 | ------------------------
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66 | 66 |
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67 |
| -Lambda is being developed by ` Hannes Hauswedell < mailto:[email protected]>`__ , but it incorporates a lot of work from other members of the `SeqAn project <http://www.seqan.de>`__. |
| 67 | +Lambda is developed by `Hannes Hauswedell <mailto:h2 (æð) fsfe.org>`__ and `Sara Hetzel <mailto:hetzel (æð) molgen.mpg.de>`__ . |
68 | 68 |
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69 | 69 | +------------------------------------------------------------------------------------------------------------------+--------------------------------------------------------------------------------------------------------------------+
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70 | 70 | | **Please always cite the publication, also if using Lambda in comparisons and pipelines** |
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@@ -92,8 +92,8 @@ feedback & updates
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92 | 92 | | :width: 76px | |
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93 | 93 | +-------------------------------------------------------------------------------------------------------------------+--------------------------------------------------------------------------------------------------------------------+
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94 | 94 | | .. image:: https://raw.githubusercontent.com/seqan/lambda/gh-pages/images_readme/appbar.email.png | To stay up to date via e-mail, please subscribe to the |
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95 |
| -| :alt: Newsletter | `newsletter <https://lists.fu-berlin.de/listinfo/lambda-users>`__. There is on average less than one e-mail | |
96 |
| -| :target: https://lists.fu-berlin.de/listinfo/lambda-users | per month. | |
| 95 | +| :alt: Newsletter | `newsletter <https://lists.fu-berlin.de/listinfo/lambda-users>`__. There is very low traffic! | |
| 96 | +| :target: https://lists.fu-berlin.de/listinfo/lambda-users | | |
97 | 97 | | :width: 76px | |
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98 | 98 | +-------------------------------------------------------------------------------------------------------------------+--------------------------------------------------------------------------------------------------------------------+
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99 | 99 | | .. image:: https://raw.githubusercontent.com/seqan/lambda/gh-pages/images_readme/appbar.social.twitter.png | You can also follow SeqAn on `twitter <https://twitter.com/SeqAnLib>`__ to receive updates on Lambda. |
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