Question about integrating unpaired data

[huziouziou]

https://kzhang.org/SnapATAC2/tutorials/annotation.html
In this tutorial’s pipeline for annotating scATAC-seq data using scRNA-seq data, is it suitable for integrating unpaired scRNA-seq and scATAC-seq datasets? I’m currently doing this, but I’m unsure whether it’s a robust approach or if using a tool like GLUE (which is explicitly designed for unpaired data) would be more appropriate.
Additionally, is the data format generated by SnapATAC2 directly compatible with GLUE’s input requirements?