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DESCRIPTION
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Package: methylSig
Title: MethylSig: Differential Methylation Testing for WGBS and RRBS Data
Version: 1.17.0
Date: 2020-04-22
Authors@R:
c(person(given = "Yongseok",
family = "Park",
role = "aut",
email = "[email protected]"),
person(given = "Raymond G.",
family = "Cavalcante",
role = c("aut", "cre"),
email = "[email protected]"))
Description: MethylSig is a package for testing for
differentially methylated cytosines (DMCs) or regions (DMRs) in
whole-genome bisulfite sequencing (WGBS) or reduced representation
bisulfite sequencing (RRBS) experiments. MethylSig uses a beta
binomial model to test for significant differences between groups of
samples. Several options exist for either site-specific or sliding
window tests, and variance estimation.
Depends:
R (>= 3.6)
Imports:
bsseq,
DelayedArray,
DelayedMatrixStats,
DSS,
IRanges,
GenomeInfoDb,
GenomicRanges,
methods,
parallel,
stats,
S4Vectors
Suggests:
BiocStyle,
bsseqData,
knitr,
rmarkdown,
testthat (>= 2.1.0),
covr
License: GPL-3
BugReports: https://github.com/sartorlab/methylSig/issues
biocViews: DNAMethylation, DifferentialMethylation, Epigenetics,
Regression, MethylSeq
Encoding: UTF-8
LazyData: true
VignetteBuilder: knitr
RoxygenNote: 7.1.0