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BTK - re-implementation #97

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DLBPointon opened this issue Feb 25, 2025 · 1 comment
Open

BTK - re-implementation #97

DLBPointon opened this issue Feb 25, 2025 · 1 comment

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@DLBPointon
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Currently we are running btk on the entire assembly, however, this is an expensive process and so we need to think about other ways to run this.

@DLBPointon
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DLBPointon commented Feb 25, 2025

Potential implementations which could all lead to a reduction in computational load are:

  • Filter by length of scaffold < 90mb

  • Filter by tag from Tiara/FCS-gx - Contaminant sequence containing scaffolds are extracted and run through BTK alone (loss of genomic context which may make the above a preferable option) - Could lead to a dramatic reduction in computational load.

  • Option to run as standard

  • Other options?

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