Currently, this repository gives two options: Nextcloud hosted by Apache in a single container, or using PHP FPM with an additional Nginx container.
Recently, there is a newer way of building high performing PHP container, which is FrankenPHP. FrankenPHP is a modern PHP webserver which is based on Caddy. The benefit of FrankenPHP is that it is incredibly fast and you only need a single container.
If there's is an interest, I would be happy to see if I can create Dockerfiles to start supporting Nextcloud based on FrankenPHP.