Questions about Mutalyzer and HGVS nomenclature

[harryiland]

Two TET2 variants in cis were obtained: NM_001127208.2:c.1484_1486del and NM_001127208.2:c.1489del

According to HGVS recommendations, these should be described as: NM_001127208.2:c.[1484_1486del;1489del] and the protein changes should be described as p.[Thr495del;Thr497Leufs*36]

However Mutalyzer converts this to NM_001127208.2:c.1484_1489delinsTG p.Thr495Metfs*37

Is this a failure of Mutalyzer or is the delins nomenclature acceptable?

Thanks