-
Notifications
You must be signed in to change notification settings - Fork 1
/
Copy pathDESCRIPTION
58 lines (58 loc) · 2.24 KB
/
DESCRIPTION
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
Package: CTCF
Title: Genomic coordinates of CTCF binding sites, with orientation
Version: 0.99.11
Authors@R: c(
person(given = "Mikhail",
family = "Dozmorov",
role = c("aut", "cre"),
email = "[email protected]",
comment = c(ORCID = "0000-0002-0086-8358")),
person(given = "Eric",
family = "Davis",
role = c("aut")),
person(given = "Wancen",
family = "Mu",
role = c("aut")),
person(given = "Stuart",
family = "Lee",
role = c("aut")),
person(given = "Tim",
family = "Triche",
role = c("aut")),
person(given = "Douglas",
family = "Phanstiel",
role = c("aut")),
person(given = "Michael",
family = "Love",
role = c("aut"))
)
Description: Genomic coordinates of CTCF binding sites, with strand orientation
(directionality of binding). Position weight matrices (PWMs) from JASPAR,
HOCOMOCO, CIS-BP, CTCFBSDB, SwissRegulon, Jolma 2013, were used to uniformly
predict CTCF binding sites using FIMO (default settings) on human
(hg18, hg19, hg38, T2T) and mouse (mm9, mm10, mm39) genome assemblies.
Extra columns include motif/PWM name (e.g., MA0139.1), score, p-value,
q-value, and the motif sequence. It is recommended to filter FIMO-predicted
sites by 1e-6 p-value threshold instead of using the default 1e-4 threshold.
Experimentally obtained CTCF-bound cis-regulatory elements from ENCODE SCREEN
and predicted CTCF sites from CTCFBSDB are also included. Selected data are
lifted over from a different genome assembly as we demonstrated liftOver
is a viable option to obtain CTCF coordinates in different genome assemblies.
CTCF sites obtained using JASPAR's MA0139.1 PWM and filtered at 1e-6 p-value
threshold are recommended.
License: MIT + file LICENSE
Encoding: UTF-8
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.2.0
URL: https://github.com/dozmorovlab/CTCF
BugReports: https://github.com/dozmorovlab/CTCF/issues
Suggests:
BiocStyle,
rmarkdown,
knitr,
AnnotationHub,
GenomicRanges,
plyranges,
sessioninfo
VignetteBuilder: knitr
biocViews: AnnotationData, AnnotationHub, FunctionalAnnotation, GenomicSequence