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error Killed java $before -jar $PROG/../share/halign-stmsa.jar $after #5

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Thtcare opened this issue Sep 25, 2024 · 1 comment
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@Thtcare
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Thtcare commented Sep 25, 2024

I run with command
halign -o merge_genome_dna.aln -t 20 -Xmx1000g merge_genome_dna.fna
that merge_genome_dna.fna contain 2 sequence that first sequence length=8,735,486 and second sequence length = 7,023,957
that error
reading merge_genome_dna.fna... finished in 209 ms
suffix tree: 4985 ms
name: 7319 ms
anti-name: 11 ms
/miniconda3/envs/halign/bin/halign: line 56: 2434645 Killed java $before -jar $PROG/../share/halign-stmsa.jar $after
how should i slove this problem?
thank you

@metaphysicser
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@Thtcare , Thank you for reporting the issue.

The problem is likely due to the length of the sequences being aligned, which causes a memory overflow during the dynamic programming process. In the next version of HAlign, we are considering incorporating the Wavefront Alignment Algorithm (WFA) to address such issues. In the meantime, we recommend using WFA2-lib or other software to perform the alignment of these large sequences.

Please let us know if you have any further questions.

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