diff --git a/nile/utils/uninstall.py b/nile/utils/uninstall.py
index 1eee27d..0371b49 100644
--- a/nile/utils/uninstall.py
+++ b/nile/utils/uninstall.py
@@ -29,7 +29,19 @@ def uninstall(self):
 
         files = self.manifest.packages[0].files
         for f in files:
-            os.remove(os.path.join(installed_info["path"], f.path.replace("\\", "/")))
+            # Manifest can contain both kind of slash as a separator on the same entry
+            os.remove(os.path.join(installed_info["path"], f.path.replace("\\", os.sep).replace("/", os.sep)))
+
+        # Remove empty directories under the installation directory
+        for dirpath, dirnames, filenames in os.walk(installed_info["path"], topdown=False):
+            for dirname in dirnames:
+                full_path = os.path.join(dirpath, dirname)
+                if not os.listdir(full_path):
+                    os.rmdir(full_path)
+
+        # Remove installation directory if it's empty
+        if not os.listdir(installed_info["path"]):
+            os.rmdir(installed_info["path"])
 
         self.config.write("installed", installed_games)
         self.config.remove(f"manifests/{game_id}", cfg_type=ConfigType.RAW)