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Removing peptide from sense/antisence chain cause unnessussary phosphate removal #6471

Closed
Tracked by #6602
AlexeyGirin opened this issue Feb 10, 2025 · 1 comment · Fixed by #6486 or #6490
Closed
Tracked by #6602

Removing peptide from sense/antisence chain cause unnessussary phosphate removal #6471

AlexeyGirin opened this issue Feb 10, 2025 · 1 comment · Fixed by #6486 or #6490
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@rrodionov91
Labels
Antisense Bucket: Antisense related issues Priority: High Sequence mode Bucket: Sequence mode related issues Severity: High High level visibility to the user
Milestone
Ketcher 3.1.0-rc.3

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@AlexeyGirin
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Steps to Reproduce

  1. Go to Macro - Sequence mode (clean canvas)
  2. Load from HELM: RNA1{R(A)P}|RNA2{R(U)P.R(U)}|PEPTIDE1{E.E}|RNA3{R(A)}$RNA1,RNA2,2:pair-2:pair|RNA1,PEPTIDE1,3:R2-1:R1|PEPTIDE1,RNA3,2:R2-1:R1|RNA3,RNA2,2:pair-5:pair$$$V2.0
    Image
  3. Click between E symbols to switch to Edit mode
  4. Press Backspace key to delete left E

Actual behavior
System turns left nucleotide into nucleoside
Image
Image

Expected behavior
System turns remain nucleotide as it is (E is deleted)
Image
Image

Versions

  • Ketcher Version 3.1.0-rc.2 Build at 2025-02-07; 15:09:23
  • Indigo Version 1.29.0-rc.1.0-g2e30df8f7-wasm32-wasm-clang-19.0.0
  • Chrome Version 133.0.6943.54 (Official Build) (64-bit)
  • Win10

Issue found while testing: #5942
@AlexeyGirin AlexeyGirin added Antisense Bucket: Antisense related issues Priority: High Sequence mode Bucket: Sequence mode related issues Severity: High High level visibility to the user labels Feb 10, 2025
@AlexeyGirin AlexeyGirin added this to the Ketcher 3.1.0-rc.3 milestone Feb 10, 2025
@rrodionov91 rrodionov91 self-assigned this Feb 11, 2025
rrodionov91 added a commit that referenced this issue Feb 11, 2025
@rrodionov91
#6471 - Removing peptide from sense/antisence chain cause unnessussar…
b548076 
…y phosphate removal
@rrodionov91 rrodionov91 linked a pull request Feb 11, 2025 that will close this issue
#6471 - Removing peptide from sense/antisence chain cause unnessussary phosphate removal #6486
Merged
9 tasks
rrodionov91 added a commit that referenced this issue Feb 11, 2025
@rrodionov91
#6471 - Removing peptide from sense/antisence chain cause unnessussar…
2faa694 
…y phosphate removal (#6486)
rrodionov91 added a commit that referenced this issue Feb 11, 2025
@rrodionov91
#6471 - Removing peptide from sense/antisence chain cause unnessussar…
eb2cda1 
…y phosphate removal (#6486)

(cherry picked from commit 2faa694)
rrodionov91 added a commit that referenced this issue Feb 11, 2025
@rrodionov91
#6471 - Removing peptide from sense/antisence chain cause unnessussar…
5fe58d0 
…y phosphate removal (#6486)

(cherry picked from commit 2faa694)
@rrodionov91 rrodionov91 linked a pull request Feb 11, 2025 that will close this issue
Backmerge: #6471 - Removing peptide from sense/antisence chain cause unnessussary phosphate removal #6490
Merged
9 tasks
@AlexeyGirin
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AlexeyGirin commented Feb 12, 2025 •
edited
Loading

Verified.
Image
Image

  • Ketcher Version 3.1.0-rc.3 Build at 2025-02-11; 20:29:49
  • Indigo Version 1.29.0-rc.1.0-g2e30df8f7-wasm32-wasm-clang-19.0.0
  • Chrome Version 133.0.6943.60 (Official Build) (64-bit)
  • Win10

rrodionov91 added a commit that referenced this issue Feb 12, 2025
@rrodionov91
Backmerge: #6471 - Removing peptide from sense/antisence chain cause …
128d4f7 
…unnessussary phosphate removal (#6490)
@AlexeyGirin AlexeyGirin mentioned this issue Mar 4, 2025
Closed
26 tasks
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Assignees

@rrodionov91 rrodionov91

Labels
Antisense Bucket: Antisense related issues Priority: High Sequence mode Bucket: Sequence mode related issues Severity: High High level visibility to the user
Projects
None yet
Milestone
Ketcher 3.1.0-rc.3
2 participants
@rrodionov91 @AlexeyGirin