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@@ -457,7 +451,7 @@ If it outputs something that starts with `flags`, the CPU can run AVX2 programs.
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## <aname="limit"></a> Limitations and Notes
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* Our accelerated kernels do not support spliced long reads. For example, acceleration of `minimap2 -ax splice ref.fa tgt.fa` is not yet supported.
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* Our accelerations are not yet integrated into the software. The code in this repository contains kernels for the chaining function itself, which can be driven by testbed generated chaining data. File input and output takes significant time in benchmarking, and we don’t count the time in the kernel execution. To achieve end-to-end acceleration, integration is required.
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* Our accelerations are not yet integrated into the software. The code in this repository contains kernels for the chaining function itself, which can be driven by testbed generated chaining data. File input and output takes significant time in benchmarking, and we don’t count the time as part of the kernel execution. To achieve end-to-end acceleration, integration is required.
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* We use an assumption that the quality of output does not degrade when we choose the lookup depth of the dynamic programming algorithm to be 64, based on the claim in Li, H. (2018).
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* We inherit most of [limitations of Minimap2][35].
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* For integration, we recommend implementing the whole `mm_chain_dp` function in all accelerations solutions to reduce output communication. The reason we choose the score value as the output point is that we can better evaluate the correctness in fine grain. We also recommend integrating the seeding part.
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