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.gitignore

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.idea/*
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.ds_store
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!Build/
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#/.build/
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#
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## Module::Build
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#build/
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#build/html/*
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#build
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#Build.bat
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#
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#```
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#build/html/*
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#*.doctree
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#*.js
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#*.html
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#build/doctrees/_templates/custom_module.doctree
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build/*
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/build/
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*.html

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source/cell.png

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source/conf.py

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# Configuration file for the Sphinx documentation builder.
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#
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# This file only contains a selection of the most common options. For a full
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# list see the documentation:
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# https://www.sphinx-doc.org/en/master/usage/configuration.html
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# -- Path setup --------------------------------------------------------------
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# If extensions (or modules to document with autodoc) are in another directory,
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# add these directories to sys.path here. If the directory is relative to the
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# documentation root, use os.path.abspath to make it absolute, like shown here.
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#
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import os
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import sys
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#sys.path.insert(0, os.path.abspath("../../src"))
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import datetime
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# -- Project information -----------------------------------------------------
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year = datetime.date.today().year
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project = "The Dean Lab"
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copyright = "2023, Dean Lab, UT Southwestern Medical Center"
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copyright = f"{year}, Dean Lab, UT Southwestern Medical Center"
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author = "Dean Lab, UT Southwestern Medical Center"
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# -- General configuration ---------------------------------------------------
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# Add any Sphinx extension module names here, as strings. They can be
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# extensions coming with Sphinx (named 'sphinx.ext.*') or your custom
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# ones.
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# extensions = [
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# "sphinx.ext.duration",
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# "sphinx.ext.doctest",
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# "sphinx.ext.autodoc",
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# "sphinx.ext.autosummary",
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# "sphinx.ext.githubpages",
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# "sphinx.ext.napoleon",
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# "sphinx.ext.coverage",
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# "sphinx_toolbox.collapse",
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# "sphinx.ext.autosectionlabel",
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# ]
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autosectionlabel_prefix_document = True
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# Boolean indicating whether to scan all found documents for
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# autosummary directives, and to generate stub pages for each
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# (http://sphinx-doc.org/latest/ext/autosummary.html)
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autosummary_generate = False
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# Both the class’ and the __init__ method’s docstring are concatenated
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autodoc_inherit_docstrings = True
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# Add any paths that contain templates here, relative to this directory.
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templates_path = ["./_templates"]
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# The suffix of source filenames.
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source_suffix = ".rst"
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# so a file named "default.css" will overwrite the builtin "default.css".
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# html_static_path = ["_static"]
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html_logo = "dean_lab.png"
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html_logo = "cell.png"
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pygments_style = "sphinx"

source/index.rst

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.. _dean-lab-home:
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######################################################
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####################
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The Dean Lab at UTSW
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######################################################
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.. image:: 2024-01-09-LungExpansion2.png
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:width: 100%
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:alt: An expanded mouse lung imaged with Axially Swept Light-Sheet Microscopy
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:align: center
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####################
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The Dean Lab is a multi-disciplinary team of biologists, chemists, physicists, and engineers
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at the University of Texas Southwestern Medical Center in Dallas, Texas. We develop
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of their native environment, and how these decisions go awry in disease. More information
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about our research can be found on our `website <https://www.dean-lab.org>`_.
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**Projects**
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=============
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---------------
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**Research Projects**
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=====================
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- Light-sheet microscopy software packages for intelligent imaging of complex tissue samples
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- `navigate <https://thedeanlab.github.io/navigate/>`_ - Light-sheet microscopy software packages for intelligent imaging of complex tissue samples. navigate is equipped with a series of plugins that extend its functionality, enabling the use of `robotics <https://github.com/TheDeanLab/navigate-at-scale>`_, imaging cells in a `projection format <https://github.com/TheDeanLab/navigate-confocal-projection>`_, accessing additional `hardware <https://github.com/TheDeanLab/navigate-mmcore-plugin>`_, and leveraging real-time feedback from `ilastik <https://github.com/TheDeanLab/navigate-ilastik-server>`_. To enable users to generate their own plugins, we provide a `plugin template <https://github.com/TheDeanLab/navigate-plugin-template>`_.
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- Tissue clearing and labeling protocols for high-resolution imaging deep within
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biological specimens.
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- `Altair <https://thedeanlab.github.io/altair/>`_ - A series of cost-effective, easy-to-assemble, and performant light-sheet microscopes for interrogating cells and tissues at the highest resolution.
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---------------
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- Cost-effective, easy-to-assemble, and performant light-sheet microscopes for interrogating live cells,
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expanded, and cleared tissue samples.
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**Educational Resources**
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================
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=========================
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- `CI2023 <https://github.com/TheDeanLab/CI2023>`_ - An introduction to continuous integration and continuous deployment for scientific software.
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---------------
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**Publication Repositories**
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================
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============================
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For many manuscripts published over the years, we provide access to CAD files, software, and data
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via GitHub. These repositories are organized by publication year.
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- `2015, Dean <https://github.com/AdvancedImagingUTSW/manuscripts/tree/main/2015-dean>`_ - Deconvolution-free subcellular imaging with axially swept light sheet microscopy.
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- `2016, Dean <https://github.com/AdvancedImagingUTSW/manuscripts/tree/main/2016-dean>`_ - Diagonally scanned light-sheet microscopy for fast volumetric imaging of adherent cells.
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- `2016, Welf <https://github.com/AdvancedImagingUTSW/manuscripts/tree/main/2016-welf-meSPIM>`_ - Quantitative multiscale cell imaging in controlled 3D microenvironments.
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- `2019, Chakraborty <https://github.com/AdvancedImagingUTSW/manuscripts/tree/main/2019-chakraborty>`_ - Light-sheet microscopy of cleared tissues with isotropic, subcellular resolution.
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- `2020, Chang <https://github.com/AdvancedImagingUTSW/manuscripts/tree/main/2020-chang-systematic-comparison>`_ - Systematic and quantitative comparison of lattice and Gaussian light-sheets.
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- `2020, Sapoznik <https://github.com/AdvancedImagingUTSW/manuscripts/tree/main/2020-sapoznik-oblique-plane-microscopy>`_ - A versatile oblique plane microscope for large-scale and high-resolution imaging of subcellular dynamics.
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- `2021, Chang <https://github.com/AdvancedImagingUTSW/manuscripts/tree/main/2021-chang-projection>`_ - Real-time multi-angle projection imaging of biological dynamics.
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- `2022, Dean <https://github.com/AdvancedImagingUTSW/manuscripts/tree/main/2021-dean-protocol>`_ - Isotropic imaging across spatial scales with axially swept light-sheet microscopy.
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- `2022, Chang <https://github.com/AdvancedImagingUTSW/manuscripts/tree/main/2022-chen>`_ - Resolution doubling in light-sheet microscopy via oblique plane structured illumination.
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- `2023, Chang <https://github.com/AdvancedImagingUTSW/manuscripts/tree/main/2023-POPSIM>`_ - Projective oblique plane structured illumination microscopy.
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- `TBD, Isogai <https://github.com/AdvancedImagingUTSW/manuscripts/tree/main/2022-isogai>`_ - Direct Arp2/3-vinculin binding is essential for cell spreading, but only on compliant substrates and in 3D.
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**Funding**
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============
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via GitHub. These repositories are organized by publication year. You can find this information :ref:`publications-home`.
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---------------
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**Our Supporters**
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==================
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The **Dean Lab** is supported by the following funding sources:
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- `UTSW President's Research Council <https://engage.utsouthwestern.edu/pages/membership-giving/membership-giving---presidents-research-council>`_
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.. toctree::
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:caption: Software
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:caption: Repositories
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:maxdepth: 2
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navigate <https://github.com/TheDeanLab/navigate>
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navigate Plugin Template <https://github.com/TheDeanLab/navigate-plugin-template>
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navigate Confocal Projection Plugin <https://github.com/TheDeanLab/navigate-confocal-projection>
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navigate At Scale <https://github.com/TheDeanLab/navigate-at-scale>
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navigate MMCore Plugin <https://github.com/TheDeanLab/navigate-mmcore-plugin>
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navigate ilastik Server <https://github.com/TheDeanLab/navigate-ilastik-server>
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navigate <https://thedeanlab.github.io/navigate/>
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altair <https://thedeanlab.github.io/altair/>
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source/publications.rst

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.. _publications-home:
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########################
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Publication Repositories
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########################
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A list of our publications with links to the associated GitHub repositories. These repositories
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contain the source code, data, and CAD files associated with the publication. A comprehensive list of our publications can be found on our website at `www.dean-lab.org <www.dean-lab.org>`_, `Google Scholar <https://scholar.google.com/citations?user=Uv0B5xIAAAAJ&hl>`_, or `PubMed <https://www.ncbi.nlm.nih.gov/myncbi/kevin.dean.1/bibliography/public/>`_.
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- `2015, Dean <https://github.com/AdvancedImagingUTSW/manuscripts/tree/main/2015-dean>`_ - Deconvolution-free subcellular imaging with axially swept light sheet microscopy.
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- `2016, Dean <https://github.com/AdvancedImagingUTSW/manuscripts/tree/main/2016-dean>`_ - Diagonally scanned light-sheet microscopy for fast volumetric imaging of adherent cells.
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- `2016, Welf <https://github.com/AdvancedImagingUTSW/manuscripts/tree/main/2016-welf-meSPIM>`_ - Quantitative multiscale cell imaging in controlled 3D microenvironments.
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- `2019, Chakraborty <https://github.com/AdvancedImagingUTSW/manuscripts/tree/main/2019-chakraborty>`_ - Light-sheet microscopy of cleared tissues with isotropic, subcellular resolution.
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- `2020, Chang <https://github.com/AdvancedImagingUTSW/manuscripts/tree/main/2020-chang-systematic-comparison>`_ - Systematic and quantitative comparison of lattice and Gaussian light-sheets.
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- `2020, Sapoznik <https://github.com/AdvancedImagingUTSW/manuscripts/tree/main/2020-sapoznik-oblique-plane-microscopy>`_ - A versatile oblique plane microscope for large-scale and high-resolution imaging of subcellular dynamics.
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- `2021, Chang <https://github.com/AdvancedImagingUTSW/manuscripts/tree/main/2021-chang-projection>`_ - Real-time multi-angle projection imaging of biological dynamics.
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- `2022, Dean <https://github.com/AdvancedImagingUTSW/manuscripts/tree/main/2021-dean-protocol>`_ - Isotropic imaging across spatial scales with axially swept light-sheet microscopy.
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- `2022, Chang <https://github.com/AdvancedImagingUTSW/manuscripts/tree/main/2022-chen>`_ - Resolution doubling in light-sheet microscopy via oblique plane structured illumination.
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- `2023, Chang <https://github.com/AdvancedImagingUTSW/manuscripts/tree/main/2023-POPSIM>`_ - Projective oblique plane structured illumination microscopy.
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- `TBD, Isogai <https://github.com/AdvancedImagingUTSW/manuscripts/tree/main/2022-isogai>`_ - Direct Arp2/3-vinculin binding is essential for cell spreading, but only on compliant substrates and in 3D.

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