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zika-hla.html
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<!DOCTYPE html>
<html lang="en">
<head>
<meta http-equiv="Content-Type" content="text/html; charset=UTF-8">
<meta charset="utf-8">
<meta http-equiv="X-UA-Compatible" content="IE=edge">
<meta name="viewport" content="width=device-width, initial-scale=1">
<meta name="description" content="">
<meta name="author" content="">
<link rel="shortcut icon" href="//igv.org/web/img/favicon.ico">
<title>ImmuneRegulation</title>
<!-- Bootstrap CSS - NOT REQUIRED FOR IGV -->
<link rel="stylesheet" type="text/css" href="https://maxcdn.bootstrapcdn.com/bootstrap/3.3.7/css/bootstrap.min.css">
<!-- jQuery UI CSS -->
<link rel="stylesheet" type="text/css" href="//ajax.googleapis.com/ajax/libs/jqueryui/1.11.2/themes/smoothness/jquery-ui.css"/>
<!-- Font Awesome CSS -->
<link rel="stylesheet" type="text/css" href="https://maxcdn.bootstrapcdn.com/font-awesome/4.2.0/css/font-awesome.min.css">
<link rel="shortcut icon" href="//igv.org/web/img/favicon.ico">
<!-- IGV CSS -->
<link rel="stylesheet" type="text/css" href="https://igv.org/web/beta/igv.css">
<!-- DataTables CSS -->
<link rel="stylesheet" type="text/css" href="//cdn.datatables.net/1.10.13/css/jquery.dataTables.css">
<link rel="stylesheet" type="text/css" src="./css/typeahead.css">
<!--link rel="stylesheet" type="text/css" src="./css/jquery.dataTables.min.css"-->
<!-- jQuery JS -->
<script type="text/javascript" src="https://ajax.googleapis.com/ajax/libs/jquery/2.0.3/jquery.min.js"></script>
<script type="text/javascript" src="https://ajax.googleapis.com/ajax/libs/jqueryui/1.11.2/jquery-ui.min.js"></script>
<!-- Bootstrap JS - NOT REQUIRED FOR IGV -->
<script src="https://maxcdn.bootstrapcdn.com/bootstrap/3.3.7/js/bootstrap.min.js"></script>
<!-- IGV JS - Deneme DEV -->
<script src="./js/igv-immuneregulation.js"></script>
<!-- D3 JS -->
<script src='https://d3js.org/d3.v3.min.js'></script>
<script src="https://labratrevenge.com/d3-tip/javascripts/d3.tip.v0.6.3.js"></script>
<!-- Bootstrap Multi-Select -->
<script src="https://cdnjs.cloudflare.com/ajax/libs/bootstrap-multiselect/0.9.13/js/bootstrap-multiselect.min.js" integrity="sha256-1fK87Pt9T7XXn/Vj3CWSfJlZkL5f73092A8YL7p7avc=" crossorigin="anonymous"></script>
<link rel="stylesheet" href="https://cdnjs.cloudflare.com/ajax/libs/bootstrap-multiselect/0.9.13/css/bootstrap-multiselect.css" integrity="sha256-O1jJhOIWWDc3wq75g7aXDl7aEQT2XPkieX/Mz/u4hQ0=" crossorigin="anonymous"/>
<!-- DataTables JS -->
<script type="text/javascript" charset="utf8" src="//cdn.datatables.net/1.10.13/js/jquery.dataTables.js"></script>
<script src="./js/underscore-min.js"></script>
<script src="./js/type.js"></script>
<script src="./js/genenames.js"></script>
<!--script type="text/javascript" charset="utf8" src="./js/jquery.dataTables.min.js"></script-->
<style type="text/css">
#custom-search-input {
margin:0;
margin-top: 10px;
padding: 0;
}
#custom-search-input .search-query {
padding-right: 3px;
padding-right: 4px \9;
padding-left: 3px;
padding-left: 4px \9;
/* IE7-8 doesn't have border-radius, so don't indent the padding */
margin-bottom: 0;
-webkit-border-radius: 3px;
-moz-border-radius: 3px;
border-radius: 3px;
}
#custom-search-input button {
border: 0;
background: none;
/** belows styles are working good */
padding: 2px 5px;
margin-top: 2px;
position: relative;
left: -28px;
/* IE7-8 doesn't have border-radius, so don't indent the padding */
margin-bottom: 0;
-webkit-border-radius: 3px;
-moz-border-radius: 3px;
border-radius: 3px;
color:#D9230F;
}
.search-query:focus + button {
z-index: 3;
}
.graph-svg-component {
background-color: AliceBlue;
}
.filter {
display: inline-block;
}
#geneSearch {
background: #1974B8;
}
#geneSearch:hover {
background: #035b9c;
}
#geneSearch:active {
background: #1974B8;
}
.btn, .btn-primary {
background: white;
padding: 14px 24px;
font-weight: 400;
letter-spacing: 1px;
border-radius: 0;
border: 1 solid;
border-color: #bbb;
}
.btn-group, .btn-group-vertical {
margin-left: 10px;
}
.btn:focus, .btn:active:focus, .btn.active:focus {
outline: 0 none;
border: 2 solid;
border-color: #bbb;
}
.btn-primary.active, .btn-primary:focus, .btn-primary:active, .open > .dropdown-toggle.btn-primary {
background: lightgray;
color: #000;
box-shadow: none;
border: 1 solid;
border-color: #bbb;
}
.btn-primary:hover {
background: #bbb;
border: 1 solid;
border-color: #bbb;
}
.btn-primary:active, .btn-primary.raised.active {
background: lightgray;
box-shadow: none;
margin-bottom: -3px;
margin-top: 3px;
border: 1 solid;
border-color: #bbb;
}
.btn-primary.disabled, .btn-primary.disabled:focus, .btn-primary.disabled:active {
background: lightgray;
color: white;
opacity: .7;
border: 1 solid;
border-color: #bbb;
}
circle {
fill-opacity: .7;
fill: rgb(30,144,255);
stroke: #aaa;
}
circle:hover {
fill: red;
stroke: #ccc;
}
caption {
font-size:medium;
text-align: center;
color: blue;
}
table {
font-size: medium;
}
path.line {
fill: none;
stroke: #666;
stroke-width: 1.5px;
}
path.area {
fill: #e7e7e7;
}
.axis {
shape-rendering: crispEdges;
}
.x.axis line {
stroke: #fff;
}
.x.axis .minor {
stroke-opacity: .5;
}
.x.axis path {
display: none;
}
.y.axis line,
.y.axis path {
fill: none;
stroke: #000;
}
.axis--y text {
font: oblique 10px Georgia, serif;
}
div.tooltip {
position: absolute;
text-align: left;
width: 160px;
height: auto;
padding: 10px;
font: 12px sans-serif;
background: lightsteelblue;
border: 0px;
border-radius: 8px;
box-shadow: 4px 4px 10px rgba(0, 0, 0, 0.4);
pointer-events: none;
}
.navbar-nav:hover {
background: #77b7ec;
}
.navbar-nav>.open {
background: #1974B8;
}
.navbar-nav > li > a:active {
font-size: larger;
}
.navbar-nav > li > a:focus {
font-size: larger;
}
.navbar-inverse .navbar-nav>.open>a, .navbar-inverse .navbar-nav>.open>a:focus, .navbar-inverse .navbar-nav>.open>a:hover {
background: #77b7ec;
}
.chart div {
font: 10px sans-serif;
background-color: steelblue;
text-align: right;
padding: 3px;
margin: 1px;
color: white;
}
.bar {
fill: lightsteelblue;
stroke: gray;
}
.bar:hover {
fill: steelblue ;
stroke: black;
}
.indbar {
fill: bisque;
stroke: gray;
}
.indbar:hover {
fill: orange ;
}
.d3-tip {
line-height: 1;
font-weight: bold;
padding: 8px;
background: rgba(255, 255, 255, 0.8);
border: 1px;
border-color: black;
color: black;
border-radius: 4px;
border: 1px solid #444;
/*border-radius: 2px;*/
}
/* Creates a small triangle extender for the tooltip */
.d3-tip:after {
box-sizing: border-box;
display: inline;
font-size: 10px;
width: 100%;
line-height: 1;
color: rgba(0, 0, 0, 0.8);
content: "\25BC";
position: absolute;
text-align: center;
}
/* Style northward tooltips differently */
.d3-tip.n:after {
margin: -1px 0 0 0;
top: 100%;
left: 0;
border: 1px;
border-color: grey;
}
</style>
<script type="text/javascript">
$(document).ready(function() {
$('#example').DataTable( {
"paging": false,
"ordering": false,
"info": false,
"filter": false
} );
} );
var HLAData = [];
d3.tsv("./data/hipc/zikv/Zika-HLA-2.tsv", function(data) {
vizHLA(data);
createHLAGraphicsA();
createHLAGraphicsB();
createHLAGraphicsC();
createHLAGraphicsDPA();
createHLAGraphicsDPB();
createHLAGraphicsDQA();
createHLAGraphicsDQB();
createHLAGraphicsDRB();
});
function vizHLA(data)
{
// Convert Data to Array:::
HLAData = _.toArray(data);
}
function createHLAGraphicsA()
{
var margin = {top: 10, right: 20, bottom: 85, left: 50},
width = 1100 - margin.left - margin.right,
height = 350 - margin.top - margin.bottom;
var x = d3.scale.ordinal()
.rangeRoundBands([0, width], .1);
var y = d3.scale.linear()
.range([height, 0]);
var xAxis = d3.svg.axis()
.scale(x)
.orient("bottom");
var yAxis = d3.svg.axis()
.scale(y)
.orient("left")
.tickFormat(d3.format("d"));
var tip = d3.tip()
.attr('class', 'd3-tip')
.offset([-10, 0])
.html(function(d) {
return "<strong>"+d.allele+"</strong>";
});
var A_Allele1 = [];
var sorted_A_Allele1 = [];
for(var i = 0; i < HLAData.length; i++)
{
var a1 = HLAData[i].HLA_A_allele1;
var a1_split = a1.split(":");
var allele1 = "HLA-" + a1_split[0] + ":" + a1_split[1];
var a2 = HLAData[i].HLA_A_allele2;
var a2_split = a2.split(":");
var allele2 = "HLA-" + a2_split[0] + ":" + a2_split[1];
A_Allele1.push(allele1);
A_Allele1.push(allele2);
}
//console.log('HLA A Allele1:::', A_Allele1);
A_Allele1.sort();
//console.log('Sorted:::', A_Allele1);
var histogramData = _.countBy(A_Allele1);
//console.log('Alleles:::', _.keys(histogramData));
//console.log('Freq:::', _.values(histogramData));
var histogramAlleles = _.toArray(_.keys(histogramData));
var histogramValues = _.toArray(_.values(histogramData));
var finalData = [];
for(var i = 0; i < histogramAlleles.length; i++)
{
var obj = {allele: histogramAlleles[i], freq:histogramValues[i]};
if(obj.allele != "HLA-:undefined")
finalData.push(obj);
}
var viz = d3.select('#chart1');
var svg = viz.append('svg')
.attr("id", "chart1-svg")
.attr("width", width + margin.left + margin.right)
.attr("height", height + margin.top + margin.bottom)
.append("g")
.attr("transform", "translate(" + margin.left + "," + margin.top + ")");
svg.call(tip);
//Generate graph...
var yval = d3.scale.linear()
.domain([0, d3.max(finalData, function(dd) { return dd.freq; })])
.range([height, 0]);
var xval = d3.scale.ordinal()
.domain(histogramAlleles.map(function(d) { return d.allele; }))
.range([width/finalData.length]);
x.domain(finalData.map(function(d) { return d.allele; }));
y.domain([0, d3.max(finalData, function(dd) { return dd.freq; })]);
svg.append("g")
.attr("class", "x axis")
.attr("transform", "translate(0," + height + ")")
.style("font-size", "small")
.call(xAxis)
.selectAll("text")
.attr("y", 0)
.attr("x", 9)
.attr("dy", ".35em")
.attr("transform", "rotate(90)")
.style("text-anchor", "start");
svg.append("g")
.attr("class", "y axis")
.call(yAxis);
svg.selectAll(".bar")
.data(finalData)
.enter().append("rect")
.attr("class", "bar")
.attr("x", function(d) { return x(d.allele); })
.attr("width", (0.85 * width)/(finalData.length+0.5))
.attr("y", function(d) {
return yval(d.freq);
})
.attr("height", function(d) {
return height - yval(d.freq);
})
.on('mouseover', tip.show)
.on('mouseout', tip.hide);
svg.append("text")
.attr("transform", "rotate(-90)")
.attr("y", 0 - margin.left)
.attr("x",0 - (height / 2))
.attr("dy", "1em")
.style("text-anchor", "middle")
.style("font-size", "medium")
.text("Counts");
}
function createHLAGraphicsB()
{
var margin = {top: 10, right: 20, bottom: 85, left: 50},
width = 1100 - margin.left - margin.right,
height = 350 - margin.top - margin.bottom;
var x = d3.scale.ordinal()
.rangeRoundBands([0, width], .1);
var y = d3.scale.linear()
.range([height, 0]);
var xAxis = d3.svg.axis()
.scale(x)
.orient("bottom");
var yAxis = d3.svg.axis()
.scale(y)
.orient("left")
.tickFormat(d3.format("d"));
var tip = d3.tip()
.attr('class', 'd3-tip')
.offset([-10, 0])
.html(function(d) {
return "<strong>"+d.allele+"</strong>";
});
var B_Allele1 = [];
var sorted_B_Allele1 = [];
for(var i = 0; i < HLAData.length; i++)
{
var a1 = HLAData[i].HLA_B_allele1;
var a1_split = a1.split(":");
var allele1 = "HLA-" + a1_split[0] + ":" + a1_split[1];
var a2 = HLAData[i].HLA_B_allele2;
var a2_split = a2.split(":");
var allele2 = "HLA-" + a2_split[0] + ":" + a2_split[1];
B_Allele1.push(allele1);
B_Allele1.push(allele2);
}
//console.log('HLA B Allele1:::', B_Allele1);
B_Allele1.sort();
//console.log('Sorted:::', B_Allele1);
var histogramData = _.countBy(B_Allele1);
//console.log('Alleles:::', _.keys(histogramData));
//console.log('Freq:::', _.values(histogramData));
var histogramAlleles = _.toArray(_.keys(histogramData));
var histogramValues = _.toArray(_.values(histogramData));
var finalData = [];
for(var i = 0; i < histogramAlleles.length; i++)
{
var obj = {allele: histogramAlleles[i], freq:histogramValues[i]};
if(obj.allele != "HLA-:undefined")
finalData.push(obj);
}
var viz = d3.select('#chart2');
var svg = viz.append('svg')
.attr("id", "chart1-svg")
.attr("width", width + margin.left + margin.right)
.attr("height", height + margin.top + margin.bottom)
.append("g")
.attr("transform", "translate(" + margin.left + "," + margin.top + ")");
svg.call(tip);
//Generate graph...
var yval = d3.scale.linear()
.domain([0, d3.max(finalData, function(dd) { return dd.freq; })])
.range([height, 0]);
var xval = d3.scale.ordinal()
.domain(histogramAlleles.map(function(d) { return d.allele; }))
.range([width/finalData.length]);
x.domain(finalData.map(function(d) { return d.allele; }));
y.domain([0, d3.max(finalData, function(dd) { return dd.freq; })]);
svg.append("g")
.attr("class", "x axis")
.attr("transform", "translate(0," + height + ")")
.style("font-size", "small")
.call(xAxis)
.selectAll("text")
.attr("y", 0)
.attr("x", 9)
.attr("dy", ".35em")
.attr("transform", "rotate(90)")
.style("text-anchor", "start");
svg.append("g")
.attr("class", "y axis")
.call(yAxis);
svg.selectAll(".bar")
.data(finalData)
.enter().append("rect")
.attr("class", "bar")
.attr("x", function(d) { return x(d.allele); })
.attr("width", (0.85 * width)/(finalData.length+0.5))
.attr("y", function(d) {
return yval(d.freq);
})
.attr("height", function(d) {
return height - yval(d.freq);
})
.on('mouseover', tip.show)
.on('mouseout', tip.hide);
svg.append("text")
.attr("transform", "rotate(-90)")
.attr("y", 0 - margin.left)
.attr("x",0 - (height / 2))
.attr("dy", "1em")
.style("text-anchor", "middle")
.style("font-size", "medium")
.text("Counts");
}
function createHLAGraphicsC()
{
var margin = {top: 10, right: 20, bottom: 85, left: 50},
width = 1100 - margin.left - margin.right,
height = 350 - margin.top - margin.bottom;
var x = d3.scale.ordinal()
.rangeRoundBands([0, width], .1);
var y = d3.scale.linear()
.range([height, 0]);
var xAxis = d3.svg.axis()
.scale(x)
.orient("bottom");
var yAxis = d3.svg.axis()
.scale(y)
.orient("left")
.tickFormat(d3.format("d"));
var tip = d3.tip()
.attr('class', 'd3-tip')
.offset([-10, 0])
.html(function(d) {
return "<strong>"+d.allele+"</strong>";
});
var C_Allele1 = [];
var sorted_C_Allele1 = [];
for(var i = 0; i < HLAData.length; i++)
{
var a1 = HLAData[i].HLA_C_allele1;
var a1_split = a1.split(":");
var allele1 = "HLA-" + a1_split[0] + ":" + a1_split[1];
var a2 = HLAData[i].HLA_C_allele2;
var a2_split = a2.split(":");
var allele2 = "HLA-" + a2_split[0] + ":" + a2_split[1];
C_Allele1.push(allele1);
C_Allele1.push(allele2);
}
//console.log('HLA C Allele1:::', C_Allele1);
C_Allele1.sort();
//console.log('Sorted:::', C_Allele1);
var histogramData = _.countBy(C_Allele1);
//console.log('Alleles:::', _.keys(histogramData));
//console.log('Freq:::', _.values(histogramData));
var histogramAlleles = _.toArray(_.keys(histogramData));
var histogramValues = _.toArray(_.values(histogramData));
var finalData = [];
for(var i = 0; i < histogramAlleles.length; i++)
{
var obj = {allele: histogramAlleles[i], freq:histogramValues[i]};
if(obj.allele != "HLA-:undefined")
finalData.push(obj);
}
var viz = d3.select('#chart3');
//console.log('Final DATA:::', finalData);
var svg = viz.append('svg')
.attr("id", "chart1-svg")
.attr("width", width + margin.left + margin.right)
.attr("height", height + margin.top + margin.bottom)
.append("g")
.attr("transform", "translate(" + margin.left + "," + margin.top + ")");
svg.call(tip);
//Generate graph...
var yval = d3.scale.linear()
.domain([0, d3.max(finalData, function(dd) { return dd.freq; })])
.range([height, 0]);
var xval = d3.scale.ordinal()
.domain(histogramAlleles.map(function(d) { return d.allele; }))
.range([width/finalData.length]);
x.domain(finalData.map(function(d) { return d.allele; }));
y.domain([0, d3.max(finalData, function(dd) { return dd.freq; })]);
svg.append("g")
.attr("class", "x axis")
.attr("transform", "translate(0," + height + ")")
.style("font-size", "small")
.call(xAxis)
.selectAll("text")
.attr("y", 0)
.attr("x", 9)
.attr("dy", ".35em")
.attr("transform", "rotate(90)")
.style("text-anchor", "start");
svg.append("g")
.attr("class", "y axis")
.call(yAxis);
svg.selectAll(".bar")
.data(finalData)
.enter().append("rect")
.attr("class", "bar")
.attr("x", function(d) { return x(d.allele); })
.attr("width", (0.8 * width)/(finalData.length+0.5))
.attr("y", function(d) {
return yval(d.freq);
})
.attr("height", function(d) {
return height - yval(d.freq);
})
.on('mouseover', tip.show)
.on('mouseout', tip.hide);
svg.append("text")
.attr("transform", "rotate(-90)")
.attr("y", 0 - margin.left)
.attr("x",0 - (height / 2))
.attr("dy", "1em")
.style("text-anchor", "middle")
.style("font-size", "medium")
.text("Counts");
}
function createHLAGraphicsDPA()
{
var margin = {top: 10, right: 20, bottom: 110, left: 50},
width = 300 - margin.left - margin.right,
height = 350 - margin.top - margin.bottom;
var x = d3.scale.ordinal()
.rangeRoundBands([0, width], .1);
var y = d3.scale.linear()
.range([height, 0]);
var xAxis = d3.svg.axis()
.scale(x)
.orient("bottom");
var yAxis = d3.svg.axis()
.scale(y)
.orient("left")
.tickFormat(d3.format("d"));
var tip = d3.tip()
.attr('class', 'd3-tip')
.offset([-10, 0])
.html(function(d) {
return "<strong>"+d.allele+"</strong>";
});
var DPA_Allele1 = [];
var sorted_DPA_Allele1 = [];
for(var i = 0; i < HLAData.length; i++)
{
var a1 = HLAData[i].HLA_DPA1_allele1;
var a1_split = a1.split(":");
var allele1 = "HLA-" + a1_split[0] + ":" + a1_split[1];
var a2 = HLAData[i].HLA_DPA1_allele2;
var a2_split = a2.split(":");
var allele2 = "HLA-" + a2_split[0] + ":" + a2_split[1];
DPA_Allele1.push(allele1);
DPA_Allele1.push(allele2);
}
//console.log('HLA DPA Allele1:::', DPA_Allele1);
DPA_Allele1.sort();
//console.log('Sorted:::', DPA_Allele1);
var histogramData = _.countBy(DPA_Allele1);
//console.log('Alleles:::', _.keys(histogramData));
//console.log('Freq:::', _.values(histogramData));
var histogramAlleles = _.toArray(_.keys(histogramData));
var histogramValues = _.toArray(_.values(histogramData));
var finalData = [];
for(var i = 0; i < histogramAlleles.length; i++)
{
var obj = {allele: histogramAlleles[i], freq:histogramValues[i]};
if(obj.allele != "HLA-:undefined")
finalData.push(obj);
}
var viz = d3.select('#chart4');
//console.log('DPA1---Final DATA:::', finalData);
var svg = viz.append('svg')
.attr("id", "chart1-svg")
.attr("width", width + margin.left + margin.right)
.attr("height", height + margin.top + margin.bottom)
.append("g")
.attr("transform", "translate(" + margin.left + "," + margin.top + ")");
svg.call(tip);
//Generate graph...
var yval = d3.scale.linear()
.domain([0, d3.max(finalData, function(dd) { return dd.freq; })])
.range([height, 0]);
var xval = d3.scale.ordinal()
.domain(histogramAlleles.map(function(d) { return d.allele; }))
.range([width/finalData.length]);
x.domain(finalData.map(function(d) { return d.allele; }));
y.domain([0, d3.max(finalData, function(dd) { return dd.freq; })]);
svg.append("g")
.attr("class", "x axis")
.attr("transform", "translate(0," + height + ")")
.style("font-size", "small")
.call(xAxis)
.selectAll("text")
.attr("y", 0)
.attr("x", 9)
.attr("dy", ".35em")
.attr("transform", "rotate(90)")
.style("text-anchor", "start");
svg.append("g")
.attr("class", "y axis")
.call(yAxis);
svg.selectAll(".bar")
.data(finalData)
.enter().append("rect")
.attr("class", "bar")
.attr("x", function(d,i) {
var rawWidth = (0.8 * width)/(finalData.length+0.5);
//if(rawWidth > 50)
// return (i * 60) + 20;
// else
return x(d.allele);
})
.attr("width", function(d) {
var rawWidth = (0.85 * width)/(finalData.length+0.5);
//if(rawWidth > 50)
// return 50;
//else
return rawWidth;
})
.attr("y", function(d) {
return yval(d.freq);
})
.attr("height", function(d) {
return height - yval(d.freq);
})
.on('mouseover', tip.show)
.on('mouseout', tip.hide);
svg.append("text")
.attr("transform", "rotate(-90)")
.attr("y", 0 - margin.left)
.attr("x",0 - (height / 2))
.attr("dy", "1em")
.style("text-anchor", "middle")
.style("font-size", "medium")
.text("Counts");
}
function createHLAGraphicsDPB()
{
var margin = {top: 10, right: 20, bottom: 115, left: 50},
width = 1100 - margin.left - margin.right,
height = 350 - margin.top - margin.bottom;
var x = d3.scale.ordinal()
.rangeRoundBands([0, width], .1);
var y = d3.scale.linear()
.range([height, 0]);
var xAxis = d3.svg.axis()
.scale(x)
.orient("bottom");
var yAxis = d3.svg.axis()
.scale(y)
.orient("left")
.tickFormat(d3.format("d"));
var tip = d3.tip()
.attr('class', 'd3-tip')
.offset([-10, 0])
.html(function(d) {
return "<strong>"+d.allele+"</strong>";
});
var DPB_Allele1 = [];
var sorted_DPB_Allele1 = [];
for(var i = 0; i < HLAData.length; i++)
{
var a1 = HLAData[i].HLA_DPB1_allele1;
var a1_split = a1.split(":");
var allele1 = "HLA-" + a1_split[0] + ":" + a1_split[1];
var a2 = HLAData[i].HLA_DPB1_allele2;
var a2_split = a2.split(":");
var allele2 = "HLA-" + a2_split[0] + ":" + a2_split[1];
DPB_Allele1.push(allele1);
DPB_Allele1.push(allele2);
}
//console.log('HLA DPB Allele1:::', DPB_Allele1);
DPB_Allele1.sort();
//console.log('Sorted:::', DPB_Allele1);
var histogramData = _.countBy(DPB_Allele1);
//console.log('Alleles:::', _.keys(histogramData));
//console.log('Freq:::', _.values(histogramData));
var histogramAlleles = _.toArray(_.keys(histogramData));
var histogramValues = _.toArray(_.values(histogramData));