Skip to content

Commit 191ff13

Browse files
committed
adding Julia's ambiguous methylation GCG fix
1 parent 1710aeb commit 191ff13

File tree

2 files changed

+3
-1
lines changed

2 files changed

+3
-1
lines changed

README.md

+2
Original file line numberDiff line numberDiff line change
@@ -2,6 +2,8 @@
22

33
## Authors
44
- Ben Doughty @bdoughty
5+
- Jason Tan @yj-tan
6+
- Julia Schaepe @juliaschaepe
57

68
## Overview:
79
The code here takes paired-end FASTQs from an amplicon SMF experiment and analyzes the single reads for methylation state. It returns both bulk measurements and single-molecule measurements, and the repo has additional code for downstream plotting. There are also scripts in `workflow/scripts` for calling binding (`classify_single_molecule_binding_v2.py`) and fitting the partition function model (`fit_partition_function_model_v3.py`).

workflow/scripts/dSMF-footprints_optional_clustering.py

+1-1
Original file line numberDiff line numberDiff line change
@@ -271,7 +271,7 @@ def run():
271271
pass
272272
else:
273273
# if GenomeDict[chr][i-1:i+2] == 'CGC':
274-
if GenomeDict[chr][i-1:i+2] == 'GCG':
274+
if GenomeDict[chr][i:i+3] == 'GCG':
275275
continue
276276
if readseq[i-pos-1:i-pos+1] == 'GC':
277277
scores[i-start] = 0

0 commit comments

Comments
 (0)