|
139 | 139 | "````{margin}\n", |
140 | 140 | "```{seealso}\n", |
141 | 141 | "[Stimulation does not elicit any response from the organoid](faq:low-response)\n", |
| 142 | + "[How are spike events obtained ? Why is the minimal inter-spike interval always 3ms ?](faq:spike-events)\n", |
142 | 143 | "```\n", |
143 | 144 | "````\n", |
144 | 145 | "\n", |
|
148 | 149 | "\n", |
149 | 150 | "A spiking rate of up to 1500 per minute is still normal (especially in the presence of bursts), but an order of magnitude more would indicate an issue with the event threshold.\n", |
150 | 151 | "\n", |
151 | | - "For instance, during a burst event, the voltage will nearly always be above the threshold, which will result in an artificial event every 3ms during the burst. However, this will show as a single event in the database, not as multiple events.\n", |
152 | | - "\n", |
| 152 | + "For instance, during a burst event, the voltage will nearly always be above the threshold, which will result in an artificial event every 3ms during the burst. However, the many spikes that occur will be merged under several events of 3ms duration.\n", |
153 | 153 | "Feel free to ask if you have further doubts regarding the activity of a channel. \n", |
154 | 154 | "\n", |
155 | 155 | "```{tip}\n", |
|
232 | 232 | "\n", |
233 | 233 | "### Database and experiment tokens\n", |
234 | 234 | "\n", |
| 235 | + "(faq:spike-events)=\n", |
| 236 | + "#### How are spike events obtained ? Why is the minimal inter-spike interval always 3ms ?\n", |
| 237 | + "\n", |
| 238 | + "````{margin}\n", |
| 239 | + "```{seealso}\n", |
| 240 | + "[How to differentiate between noise and activity?](faq:noise-vs-events)\n", |
| 241 | + "```\t\n", |
| 242 | + "````\n", |
| 243 | + "\n", |
| 244 | + "Events are recorded whenever the voltage crosses the event threshold of $6\\sigma$. This means that whenever the voltage crosses the threshold, an event is recorded for 3ms.\n", |
| 245 | + "As such, several spikes may be merged under several events, especially during bursts.\n", |
| 246 | + "\n", |
| 247 | + "```{caution}\n", |
| 248 | + "By default, the threshold is **dynamic**, which means it is computed based on the standard deviation of the noise at a certain time interval.<br>\n", |
| 249 | + "During bursts or stimulation, this standard deviation may increase, which will overall lower the amount of events recorded.<br>\n", |
| 250 | + "See [Variable threshold](np-core:variance-threshold) for more information.\n", |
| 251 | + "```\n", |
| 252 | + "\n", |
235 | 253 | "#### I do not have an Experiment token, or it is no longer valid\n", |
236 | 254 | "\n", |
237 | 255 | "Please contact us.\n", |
|
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