@@ -69,7 +69,338 @@ export const DATASETS = {
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musculoskeletal : [ ] ,
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"nervous-system" : [ ] ,
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oral : [ ] ,
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- organoid : [ ] ,
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+ "organoid-brain" : [
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+ buildDataset (
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+ [ "--" ] ,
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+ 0 ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ "Developmental excitation-inhibition imbalance underlying psychoses revealed by single-cell analyses of discordant twins-derived cerebral organoids" ,
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+ {
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+ doi : "10.1038/s41380-020-0844-z" ,
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+ officialHcaPublication : null ,
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+ publicationTitle :
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+ "Developmental excitation-inhibition imbalance underlying psychoses revealed by single-cell analyses of discordant twins-derived cerebral organoids" ,
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+ publicationUrl : "https://doi.org/10.1038/s41380-020-0844-z" ,
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+ }
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+ ) ,
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+ buildDataset (
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+ [ "--" ] ,
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+ 0 ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ "hESC-Derived Thalamic Organoids Form Reciprocal Projections When Fused with Cortical Organoids" ,
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+ {
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+ doi : "10.1016/j.stem.2018.12.015" ,
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+ officialHcaPublication : null ,
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+ publicationTitle :
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+ "hESC-Derived Thalamic Organoids Form Reciprocal Projections When Fused with Cortical Organoids" ,
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+ publicationUrl : "https://doi.org/10.1016/j.stem.2018.12.015" ,
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+ }
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+ ) ,
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+ buildDataset (
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+ [ "--" ] ,
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+ 0 ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ "Generation of Functional Human 3D Cortico-Motor Assembloids" ,
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+ {
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+ doi : "10.1016/j.cell.2020.11.017" ,
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+ officialHcaPublication : null ,
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+ publicationTitle :
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+ "Generation of Functional Human 3D Cortico-Motor Assembloids" ,
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+ publicationUrl : "https://doi.org/10.1016/j.cell.2020.11.017" ,
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+ }
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+ ) ,
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+ buildDataset (
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+ [ "--" ] ,
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+ 0 ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ "Generation of human striatal organoids and cortico-striatal assembloids from human pluripotent stem cells" ,
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+ {
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+ doi : "10.1038/s41587-020-00763-w" ,
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+ officialHcaPublication : null ,
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+ publicationTitle :
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+ "Generation of human striatal organoids and cortico-striatal assembloids from human pluripotent stem cells" ,
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+ publicationUrl : "https://doi.org/10.1038/s41587-020-00763-w" ,
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+ }
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+ ) ,
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+ buildDataset (
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+ [ "--" ] ,
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+ 0 ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ "Gruffi: an algorithm for computational removal of stressed cells from brain organoid transcriptomic datasets" ,
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+ {
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+ doi : "10.15252/embj.2022111118" ,
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+ officialHcaPublication : null ,
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+ publicationTitle :
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+ "Gruffi: an algorithm for computational removal of stressed cells from brain organoid transcriptomic datasets" ,
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+ publicationUrl : "https://doi.org/10.15252/embj.2022111118" ,
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+ }
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+ ) ,
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+ buildDataset (
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+ [ "--" ] ,
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+ 0 ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ "Midbrain_organoid_Treutlein"
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+ ) ,
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+ buildDataset (
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+ [ "--" ] ,
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+ 0 ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ "Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex" ,
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+ {
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+ doi : "10.1016/j.cell.2022.09.010" ,
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+ officialHcaPublication : null ,
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+ publicationTitle :
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+ "Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex" ,
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+ publicationUrl : "https://doi.org/10.1016/j.cell.2022.09.010" ,
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+ }
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+ ) ,
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+ buildDataset (
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+ [ "--" ] ,
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+ 0 ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ "Autism genes converge on asynchronous development of shared neuron classes" ,
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+ {
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+ doi : "10.1038/s41586-021-04358-6" ,
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+ officialHcaPublication : null ,
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+ publicationTitle :
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+ "Autism genes converge on asynchronous development of shared neuron classes" ,
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+ publicationUrl : "https://doi.org/10.1038/s41586-021-04358-6" ,
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+ }
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+ ) ,
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+ buildDataset (
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+ [ "--" ] ,
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+ 0 ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ "Generation of hypothalamic arcuate organoids from human induced pluripotent stem cells" ,
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+ {
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+ doi : "10.1016/j.stem.2021.04.006" ,
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+ officialHcaPublication : null ,
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+ publicationTitle :
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+ "Generation of hypothalamic arcuate organoids from human induced pluripotent stem cells" ,
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+ publicationUrl : "https://doi.org/10.1016/j.stem.2021.04.006" ,
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+ }
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+ ) ,
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+ buildDataset (
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+ [ "--" ] ,
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+ 0 ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ "Individual brain organoids reproducibly form cell diversity of the human cerebral cortex" ,
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+ {
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+ doi : "10.1038/s41586-019-1289-x" ,
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+ officialHcaPublication : null ,
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+ publicationTitle :
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+ "Individual brain organoids reproducibly form cell diversity of the human cerebral cortex" ,
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+ publicationUrl : "https://doi.org/10.1038/s41586-019-1289-x" ,
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+ }
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+ ) ,
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+ buildDataset (
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+ [ "--" ] ,
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+ 0 ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ "Human Astrocyte Maturation Captured in 3D Cerebral Cortical Spheroids Derived from Pluripotent Stem Cells" ,
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+ {
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+ doi : "10.1016/j.neuron.2017.07.035" ,
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+ officialHcaPublication : null ,
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+ publicationTitle :
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+ "Human Astrocyte Maturation Captured in 3D Cerebral Cortical Spheroids Derived from Pluripotent Stem Cells" ,
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+ publicationUrl : "https://doi.org/10.1016/j.neuron.2017.07.035" ,
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+ }
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+ ) ,
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+ buildDataset (
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+ [ "--" ] ,
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+ 0 ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ "Cell stress in cortical organoids impairs molecular subtype specification" ,
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+ {
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+ doi : "10.1038/s41586-020-1962-0" ,
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+ officialHcaPublication : null ,
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+ publicationTitle :
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+ "Cell stress in cortical organoids impairs molecular subtype specification" ,
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+ publicationUrl : "https://doi.org/10.1038/s41586-020-1962-0" ,
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+ }
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+ ) ,
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+ buildDataset (
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+ [ "--" ] ,
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+ 0 ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ "Differentiation and maturation of oligodendrocytes in human three-dimensional neural cultures" ,
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+ {
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+ doi : "10.1038/s41593-018-0316-9" ,
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+ officialHcaPublication : null ,
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+ publicationTitle :
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+ "Differentiation and maturation of oligodendrocytes in human three-dimensional neural cultures" ,
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+ publicationUrl : "https://doi.org/10.1038/s41593-018-0316-9" ,
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+ }
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+ ) ,
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+ buildDataset (
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+ [ "--" ] ,
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+ 0 ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ "Human CNS barrier-forming organoids with cerebrospinal fluid production" ,
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+ {
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+ doi : "10.1126/science.aaz5626" ,
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+ officialHcaPublication : null ,
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+ publicationTitle :
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+ "Human CNS barrier-forming organoids with cerebrospinal fluid production" ,
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+ publicationUrl : "https://doi.org/10.1126/science.aaz5626" ,
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+ }
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+ ) ,
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+ buildDataset (
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+ [ "--" ] ,
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+ 0 ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ "Assembly of functionally integrated human forebrain spheroids" ,
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+ {
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+ doi : "10.1038/nature22330" ,
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+ officialHcaPublication : null ,
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+ publicationTitle :
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+ "Assembly of functionally integrated human forebrain spheroids" ,
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+ publicationUrl : "https://doi.org/10.1038/nature22330" ,
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+ }
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+ ) ,
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+ buildDataset (
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+ [ "--" ] ,
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+ 0 ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ "Cerebellar_organoid_Quadrato"
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+ ) ,
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+ buildDataset (
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+ [ "--" ] ,
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+ 0 ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ "Sliced Human Cortical Organoids for Modeling Distinct Cortical Layer Formation" ,
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+ {
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+ doi : "10.1016/j.stem.2020.02.002" ,
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+ officialHcaPublication : null ,
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+ publicationTitle :
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+ "Sliced Human Cortical Organoids for Modeling Distinct Cortical Layer Formation" ,
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+ publicationUrl : "https://doi.org/10.1016/j.stem.2020.02.002" ,
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+ }
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+ ) ,
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+ buildDataset (
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+ [ "--" ] ,
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+ 0 ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ "Complex Oscillatory Waves Emerging from Cortical Organoids Model Early Human Brain Network Development" ,
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+ {
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+ doi : "10.1016/j.stem.2019.08.002" ,
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+ officialHcaPublication : null ,
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+ publicationTitle :
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+ "Complex Oscillatory Waves Emerging from Cortical Organoids Model Early Human Brain Network Development" ,
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+ publicationUrl : "https://doi.org/10.1016/j.stem.2019.08.002" ,
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+ }
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+ ) ,
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+ buildDataset (
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+ [ "--" ] ,
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+ 0 ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ "Reliability of human cortical organoid generation" ,
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+ {
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+ doi : "10.1038/s41592-018-0255-0" ,
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+ officialHcaPublication : null ,
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+ publicationTitle : "Reliability of human cortical organoid generation" ,
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+ publicationUrl : "https://doi.org/10.1038/s41592-018-0255-0" ,
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+ }
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+ ) ,
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+ buildDataset (
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+ [ "--" ] ,
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+ 0 ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ "Single-cell transcriptomics captures features of human midbrain development and dopamine neuron diversity in brain organoids" ,
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+ {
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+ doi : "10.1038/s41467-021-27464-5" ,
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+ officialHcaPublication : null ,
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+ publicationTitle :
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+ "Single-cell transcriptomics captures features of human midbrain development and dopamine neuron diversity in brain organoids" ,
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+ publicationUrl : "https://doi.org/10.1038/s41467-021-27464-5" ,
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+ }
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+ ) ,
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+ buildDataset (
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+ [ "--" ] ,
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+ 0 ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ "Inferring and perturbing cell fate regulomes in human brain organoids" ,
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+ {
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+ doi : "10.1038/s41586-022-05279-8" ,
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+ officialHcaPublication : null ,
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+ publicationTitle :
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+ "Inferring and perturbing cell fate regulomes in human brain organoids" ,
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+ publicationUrl : "https://doi.org/10.1038/s41586-022-05279-8" ,
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+ }
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+ ) ,
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+ buildDataset (
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+ [ "--" ] ,
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+ 0 ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ "ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids" ,
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+ {
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+ doi : "10.1016/j.cell.2021.07.003" ,
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+ officialHcaPublication : null ,
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+ publicationTitle :
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+ "ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids" ,
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+ publicationUrl : "https://doi.org/10.1016/j.cell.2021.07.003" ,
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+ }
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+ ) ,
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+ buildDataset (
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+ [ "--" ] ,
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+ 0 ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ [ "--" ] ,
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+ "Androgens increase excitatory neurogenic potential in human brain organoids" ,
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+ {
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+ doi : "10.1038/s41586-021-04330-4" ,
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+ officialHcaPublication : null ,
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+ publicationTitle :
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+ "Androgens increase excitatory neurogenic potential in human brain organoids" ,
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+ publicationUrl : "https://doi.org/10.1038/s41586-021-04330-4" ,
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+ }
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+ ) ,
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+ ] ,
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pancreas : [ ] ,
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reproduction : [ ] ,
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skin : [ ] ,
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